WHAT IS JWH-398 ?
JWH 398
JWH-398 is an analgesic chemical from the naphthoylindole family, which acts as a cannabinoid agonist at both the CB1 and CB2 receptors.
It has mild selectivity for CB1 with a Ki of 2.3 nM and 2.8 nM at CB2.
This synthetic chemical compound was identified by the EMCDDA as an ingredient in three separate “herbal incense” products purchased from online shops between February to June 2009.
It was discovered by, and named after, John W. Huffman
JWH 398 is an analytical reference standard categorized as a synthetic cannabinoid. JWH 398 is regulated as a Schedule I compound in the United States. This product is intended for research and forensic applications.
Technical Information
CAS Number
1292765-18-4
Molecular Formula
C24H22ClNO
Formula Weight
375.9
Purity
≥95%
Formulation(Request formulation change)
A solution in methanol
Solubility
- DMF: 5 mg/ml
- DMSO: 5 mg/ml
- Ethanol: 30 mg/ml
- Methanol: 5 mg/ml
λmax
218, 316 nm
SMILES
CCCCCN1C2=C(C=CC=C2)C(C(C3=CC=C(Cl)C4=C3C=CC=C4)=O)=C1
InChi Code
InChI=1S/C24H22ClNO/c1-2-3-8-15-26-16-21(19-11-6-7-12-23(19)26)24(27)20-13-14-22(25)18-10-5-4-9-17(18)20/h4-7,9-14,16H,2-3,8,15H2,1H3
InChi Key
IUWBHGFOHXVVKV-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 1 year
